Gun 2 back vs 4-4

Brian,
It depends who is more of a threat. If you are pitching off the force defender (outside invert) take slot wr and have him block the FS running the alley. Now you have heard pdow talk about sending his #2 or #3 wr out of trips to 1st inside 2nd level defender. The key is walling off the backside LB with the oline. Securing that puts your slot on FS which is what you want.