Gun runs vs Odd 32 front

I will be running a 4 wide gun look this fall. The question I have is the following: Versus a 32 look- nose + 2 4 technique tackles with OLB's in a walkaway position should I base block the backside end on stretch, zone plays? Here is what I see as a problem; The unblocked end closes down hard so my QB gets a pull read, and my receiver can not get a good block on the walkaway because he is aligned with heavy inside leverage. Not enough to be vulnerable to the bubble or any uncovered situation but enough that blocking him might be difficult. My RB is by far the better runner and I would like him to get the ball anyway, most of the time. I feel that by blocking that end I will get a give read and I still have the backside guard and center combo on to the WLB. Any comments would be greatly appreciated. Also I believe this same philosophy hold true against a 4-1 look. 4 linemen & 1 LB.